An investigational vaccine called rVSV-ZEBOV has shown to be highly protective against Ebola virus infection. The rVSV-ZEBOV vaccine was studied in several trials that involved more than 16,000 volunteers in Europe, Africa and the United States, and it was found to be safe and protective against the Ebola virus. The vaccine consists of a vesicular stomatitis virus (VSV), which is an animal virus that causes flulike illness in humans. The VSV has been genetically engineered to contain a protein from the Zaire Ebola virus so that it can provoke immune response to the Ebola virus.
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